Today is International Women’s Day. Please join me in celebrating some of the women who have made significant contributions to our understanding of pancreatic cancer through PanCAN Research Grants.
 Diane Simeone UCSD Moore’s Cancer Center |
Mesenchymal Stem Cells in Pancreatic Cancer Biology and Therapeutic Development Emerging frontiers in pancreatic cancer research: elaboration of key genes, cells and the extracellular milieu. [PMID: 22759592] |
 M. Celeste Simon Univ of Penn |
Role of Hif1a in inflammation, tissue repair, and cancer of the pancreas Hif1a Deletion Reveals Pro-Neoplastic Function of B Cells in Pancreatic Neoplasia.[PMID: 26715642 ] |
 Christine Iacobuzio-Donahue Memorial Sloan Kettering |
Using a Genomic Scale to Identify the Genes that Play a Role in the Ability of Pancreatic Cancer to Metastasize to Other Organs Distant metastasis occurs late during the genetic evolution of pancreatic cancer.[PMID: 20981102] |
 Stephanie Dougan DFCI |
Transnuclear mice: understanding the T cell response to pancreatic cancer Broadening the Impact of Immunotherapy to Pancreatic Cancer: Challenges and Opportunities. [PMID: 30660727] |
 Mikala Egeblad Cold Spring Harbor Laboratory |
Dynamics of Tumor-Stroma Interactions in Pancreatic Cancer Dynamic, long-term in vivo imaging of tumor-stroma interactions in mouse models of breast cancer using spinning-disk confocal microscopy. [PMID: 21285277 ] |
 Dannielle Engle Salk Institute for Biological Studies |
CA 19-9 Promotes Pancreatitis and Pancreatic Cancer Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors [PMID: 27742686] |
 Luisa Escobar-Hoyos, PhD Memorial Sloan-Kettering Cancer Center |
mRNA Splicing in Pancreatic Adenocarcinoma Aberrant RNA Splicing in Cancer. [PMID: 32864546] |
 Daria Esterházy Univ of Chicago |
Duodenal Control of Pancreatic Ductal Adenocarcinoma Compartmentalized gut lymph node drainage dictates adaptive immune responses. [PMID: 30988509] |
 Nada Kalaany Children’s Hospital Boston |
Role of arginine metabolism in obesity-associated pancreatic cancer Critical role for arginase 2 in obesity-associated pancreatic cancer. [PMID: 28808255] |
 Marina Pasca di Magliano Univ of Michigan |
Notch Signaling in Pancreatic Cancer Initiation and Progression Epithelial Notch signaling is a limiting step for pancreatic carcinogenesis. [PMID: 25416148] |
 Florencia McAllister MD Anderson Cancer Center |
Targeting IL-17 Signaling Axis in Pancreatic Ductal Adenocarcinoma Targeting IL-17 for pancreatic cancer prevention.[PMID: 25393980] |
 Rushika Perera UCSF |
Targeting Nutrient Scavenging Pathways That Fuel Pancreatic Cancer Growth Pancreatic Cancer Metabolism: Breaking It Down to Build It Back Up. [PMID: 26534901] |
 Yuliya Pylayeva-Gupta New York University |
Immunomodulatory mechanisms in Kras-driven pancreatic cancer and metastasis KRAS Mutant Pancreatic Cancer: No Lone Path to an Effective Treatment. [PMID: 27096871 ] |
 Gloria Su Columbia University |
Activin Signaling in the Development of Pancreatic Cancer Precursor Lesions Dual Roles of the Activin Signaling Pathway in Pancreatic Cancer. [PMID: 34356885 ] |
 Amy Tang Eastern Virginia Medical School |
SIAH is a Novel and Effective Anti-K-Ras Drug Target in Pancreatic Cancer A New Strategy to Control and Eradicate “Undruggable” Oncogenic K-RAS-Driven Pancreatic Cancer: Molecular Insights and Core Principles Learned from Developmental and Evolutionary Biology. [PMID: 29757973] |
 Jennifer Tseng Univ of Mass. Medical School |
Development of a Malignancy Prediction Rule for Cystic Lesions of the Pancreas Lymph node metastases in resected pancreatic ductal adenocarcinoma: predictors of disease recurrence and survival. [PMID: 28982112 ] |
 Valerie Weaver UCSF |
Interplay between tension and inflammation in pancreatic tumor progression Fibrosis and cancer: A strained relationship. [PMID: 32147542] |
 Kathryn Wellen Univ of Pennsylvania |
Understanding Metabolic Control of the Pancreatic Cancer Epigenome Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis. [PMID: 28092686 ] |
 Wantong Yao MD Anderson Cancer Center |
Syndecan-1 is a Novel Regulator for Nutrient Salvage Pathway Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer [PMID: 30918400] |