Here are the latest postings to the Pancreatic Cancer Genomics Group on Mendeley. Some of the more interesting highlights from this batch of papers include, a finding that in one paper that a Pomegranate extract was found to be more effective at cell cycle arrest than paclitaxel. And that the inhibition of RAS family members using ACE inhibitors was shown to double the length of progression free survival time in patients in a University of Tokyo study. For those of you who are interested in learning more about the form of pancreatic cancer that Steve Jobs currently suffers from, you’ll find a number of papers on Pancreatic Neurendocrine Tumors (PNET) here and in the group’s collection here.
- Cellular features of senescence during the evolution of human and murine ductal pancreatic cancer.
- Pomegranate Extract Induces Cell Cycle Arrest and Alters Cellular Phenotype of Human Pancreatic Cancer Cells.
- Palladin is a Marker of Liver Metastasis in Primary Pancreatic Endocrine Carcinomas.
- Inhibition of renin-angiotensin system affects prognosis of advanced pancreatic cancer receiving gemcitabine.
- PAX8 is expressed in pancreatic well-differentiated neuroendocrine tumors and in extrapancreatic poorly differentiated neuroendocrine carcinomas in fine-needle aspiration biopsy specimens.
- Gemcitabine Overcomes Erlotinib Resistance in EGFR-Overexpressing Cancer Cells through Downregulation of Akt.
- Increased expression of the large GTPase dynamin 2 potentiates metastatic migration and invasion of pancreatic ductal carcinoma.
- Vitamin E succinate inhibits survivin and induces apoptosis in pancreatic cancer cells.
- Insulin-like growth factor axis gene polymorphisms modify risk of pancreatic cancer.
- Increased expression of the large GTPase dynamin 2 potentiates metastatic migration and invasion of pancreatic ductal carcinoma.
- Pancreatic Neuroendocrine Tumors in Glucagon Receptor-Deficient Mice
- Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development.
- High Expression of Delta-Like Ligand 4 Predicts Poor Prognosis After Curative Resection for Pancreatic Cancer.
- Multiple genes are hypermethylated in intraductal papillary mucinous neoplasms of the pancreas.
- Cyclin Dependent Kinase 5 is amplified and over-expressed in pancreatic cancer and activated by mutant K-Ras.
- PIK3CA Mutations Frequently Coexist with RAS and BRAF Mutations in Patients with Advanced Cancers.
- The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate.
- Benzyl isothiocyanate sensitizes human pancreatic cancer cells to radiation by inducing apoptosis.
- BART inhibits pancreatic cancer cell invasion by inhibiting ARL2-mediated RhoA inactivation.
- Effects of capsid modified oncolytic adenoviruses and their combinations with gemcitabine or silica gel on pancreatic cancer.
Related articles
- Steve Jobs Resigns from Apple as CEO (onebluestocking.wordpress.com)

