Here’s this weeks crop of papers on the Pancreatic Cancer Genomics Group on Mendeley:
- PAX8 is expressed in pancreatic well-differentiated neuroendocrine tumors and in extrapancreatic poorly differentiated neuroendocrine carcinomas in fine-needle aspiration biopsy specimens.
- Gemcitabine Overcomes Erlotinib Resistance in EGFR-Overexpressing Cancer Cells through Downregulation of Akt.
- Increased expression of the large GTPase dynamin 2 potentiates metastatic migration and invasion of pancreatic ductal carcinoma.
- Vitamin E succinate inhibits survivin and induces apoptosis in pancreatic cancer cells.
- Insulin-like growth factor axis gene polymorphisms modify risk of pancreatic cancer.
- Increased expression of the large GTPase dynamin 2 potentiates metastatic migration and invasion of pancreatic ductal carcinoma.
- Pancreatic Neuroendocrine Tumors in Glucagon Receptor-Deficient Mice
- Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development.
- High Expression of Delta-Like Ligand 4 Predicts Poor Prognosis After Curative Resection for Pancreatic Cancer.
- Multiple genes are hypermethylated in intraductal papillary mucinous neoplasms of the pancreas.
- Cyclin Dependent Kinase 5 is amplified and over-expressed in pancreatic cancer and activated by mutant K-Ras.
- PIK3CA Mutations Frequently Coexist with RAS and BRAF Mutations in Patients with Advanced Cancers.
- The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate.
- Benzyl isothiocyanate sensitizes human pancreatic cancer cells to radiation by inducing apoptosis.
- BART inhibits pancreatic cancer cell invasion by inhibiting ARL2-mediated RhoA inactivation.
- Effects of capsid modified oncolytic adenoviruses and their combinations with gemcitabine or silica gel on pancreatic cancer.
- An oncolytic adenovirus defective in pRb-binding (dl922-947) can efficiently eliminate pancreatic cancer cells and tumors in vivo in combination with 5-FU or gemcitabine.
- Claudin-4 Expression Predicts Survival in Pancreatic Ductal Adenocarcinoma.
- Identification of epigenetically silenced genes in human pancreatic cancer by a novel method “microarray coupled with methyl-CpG targeted transcriptional activation” (MeTA-array).
- Genome-wide profiling of methylated promoters in pancreatic adenocarcinoma.
If you’d like to suggest additional papers, please leave a comment to the post, or join the group.